Parameters:

	Item	Compartment	Name	Parameter	Units	Comment	Scenarios:		a_00_Baseline		b_10_HighImpB	b_11_MoreNPC		c_20_LowImpA	c_22_NoImpA		d_00_NoEnergy	d_10_HighImpB	d_11_MoreNPC
							Description:		With RanGTP regeneration								Without RanGTP regeneration
									Low ImpB		Increase ImpB	Increase #NPC		Decrease ImpA	Almost no ImpA		Low ImpB	Increase ImpB	Increase #NPC
	Compartment		C	Value	picoliter	C = Vol of cytoplasm = Vol of nucleus			1		1	1		1	1		1	1	1
						Initial values
	Species	C	CAS(c)	Value	uM				1		1	1		1	1		1	1	1
	Species	C	CAS(n)	Value	uM				0		0	0		0	0		0	0	0
	Species	C	Ran·GTP(n)	Value	uM				3		3	3		3	3		3	3	3
								For the first scenario, equals to count:
	Species	C	NPC(c)	Value	uM			6000	0.01		0.01	0.1		0.01	0.01		0.01	0.01	0.1
	Species	C	NPC	Value	uM	Inner capacity		600000	1		1	10		1	1		1	1	10
	Species	C	NPC(n)	Value	uM			6000	0.01		0.01	0.1		0.01	0.01		0.01	0.01	0.1
	Species	C	ImpB(c)	Value	uM				0.05		10	10		0.05	0.05		0.05	10	10
	Species	C	ImpB(n)	Value	uM				0		0	0		0	0		0	0	0
	Species	C	ImpA(c)	Value	uM				0.5		0.5	0.5		0.1	1e-6		0.5	0.5	0.5
	Species	C	ImpA(n)	Value	uM				0.5		0.5	0.5		0.1	1e-6		0.5	0.5	0.5
						Kinetic constants
	Reaction		hydrolysis of Ran·GTP·ImpB·NPC	kf	1/s				0.1		0.1	0.1		0.1	0.1		0.1	0.1	0.1
	Reaction		hydrolysis of ImpA·CAS·Ran·GTP·NPC	kf	1/s				1e-2		1e-2	1e-2		1e-2	1e-2		1e-2	1e-2	1e-2
	Reaction		CAS with Ran	kf	1/uM/s				0.01		0.01	0.01		0.01	0.01		0.01	0.01	0.01
	Reaction		CAS with Ran	kr	1/s				0.015		0.015	0.015		0.015	0.015		0.015	0.015	0.015
	Reaction		CAS with NPC(c)	kf	1/uM/s				1e-3		1e-3	1e-3		1e-3	1e-3		1e-3	1e-3	1e-3
	Reaction		CAS with NPC(c)	kr	1/s				1e-4		1e-4	1e-4		1e-4	1e-4		1e-4	1e-4	1e-4
	Reaction		CAS with NPC(n)	kf	1/uM/s				1e-3		1e-3	1e-3		1e-3	1e-3		1e-3	1e-3	1e-3
	Reaction		CAS with NPC(n)	kr	1/s				1e-4		1e-4	1e-4		1e-4	1e-4		1e-4	1e-4	1e-4
	Reaction		CAS·Ran with ImpA	kf	1/uM/s				0.1		0.1	0.1		0.1	0.1		0.1	0.1	0.1
	Reaction		CAS·Ran with ImpA	kr	1/s	kD = 1nM			1e-4		1e-4	1e-4		1e-4	1e-4		1e-4	1e-4	1e-4
	Reaction		Complex CAS with NPC(c)	kf	1/uM/s	"Complex CAS" = ImpA·CAS·Ran·GTP			1e-3		1e-3	1e-3		1e-3	1e-3		1e-3	1e-3	1e-3
	Reaction		Complex CAS with NPC(c)	kr	1/s				1e-5		1e-5	1e-5		1e-5	1e-5		1e-5	1e-5	1e-5
	Reaction		Complex CAS with NPC(n)	kf	1/uM/s				1e-3		1e-3	1e-3		1e-3	1e-3		1e-3	1e-3	1e-3
	Reaction		Complex CAS with NPC(n)	kr	1/s				1e-5		1e-5	1e-5		1e-5	1e-5		1e-5	1e-5	1e-5
	Reaction		Replenish NLS	kf	1/s				0		0	0		0	0		0	0	0
	Reaction		Passive diffusion	k_diff	1/s				0		0	0		0	0		0	0	0
	Reaction		Ran gradient	k_pump	1/s				1e-2		1e-2	1e-2		1e-2	1e-2		0	0	0
			For uploaded results, see:
			https://numpde.github.io/nct1/code/20211018-Appli/checkpoint/