Parameters:

	Item	Compartment	Name	Parameter	Units	Comment	Scenarios:		a_Baseline		b_LowImpB		c_MoreNPC		d_HighImpA	d_LowImpA		e_NoEnergy
							Description:		With RanGTP regeneration									No RanGTP regeneration
									Physiological		Low ImpB		Increase #NPC		High ImpA	Low ImpA
	Compartment		C	Value	picoliter	C = Vol of cytoplasm = Vol of nucleus			1		1		1		1	1		1
						Initial values
	Species	C	CAS(c)	Value	uM				1		1		1		1	1		1
	Species	C	CAS(n)	Value	uM				1		1		1		1	1		1
	Species	C	Ran·GTP(n)	Value	uM				3		3		3		3	3		3
								For the first scenario, equals to count:
	Species	C	NPC(c)	Value	uM			6000	0.01		0.01		0.1		0.01	0.01		0.01
	Species	C	NPC	Value	uM	Inner capacity		600000	1		1		10		1	1		1
	Species	C	NPC(n)	Value	uM			6000	0.01		0.01		0.1		0.01	0.01		0.01
	Species	C	ImpB(c)	Value	uM				5		0.5		5		5	5		5
	Species	C	ImpB(n)	Value	uM				5		0.5		5		5	5		5
	Species	C	ImpA(c)	Value	uM				0.4		0.4		0.4		4	0.04		0.4
	Species	C	ImpA(n)	Value	uM				0.4		0.4		0.4		4	0.04		0.4
						Kinetic constants
	Reaction		hydrolysis of Ran·GTP·ImpB·NPC	kf	1/s				0.1		0.1		0.1		0.1	0.1		0.1
	Reaction		hydrolysis of ImpA·CAS·Ran·GTP(c)	kf	1/s				0.1		0.1		0.1		0.1	0.1		0.1
	Reaction		hydrolysis of ImpA·CAS·Ran·GTP·NPC	kf	1/s				0.1		0.1		0.1		0.1	0.1		0.1
	Reaction		CAS with Ran	kf	1/uM/s				0.01		0.01		0.01		0.01	0.01		0.01
	Reaction		CAS with Ran	kr	1/s				0.015		0.015		0.015		0.015	0.015		0.015
	Reaction		CAS with NPC(c)	kf	1/uM/s				1e-3		1e-3		1e-3		1e-3	1e-3		1e-3
	Reaction		CAS with NPC(c)	kr	1/s				1e-4		1e-4		1e-4		1e-4	1e-4		1e-4
	Reaction		CAS with NPC(n)	kf	1/uM/s				1e-3		1e-3		1e-3		1e-3	1e-3		1e-3
	Reaction		CAS with NPC(n)	kr	1/s				1e-4		1e-4		1e-4		1e-4	1e-4		1e-4
	Reaction		CAS·Ran with ImpA	kf	1/uM/s				0.1		0.1		0.1		0.1	0.1		0.1
	Reaction		CAS·Ran with ImpA	kr	1/s	kD = 1nM			1e-4		1e-4		1e-4		1e-4	1e-4		1e-4
	Reaction		Complex CAS with NPC(c)	kf	1/uM/s	"Complex CAS" = ImpA·CAS·Ran·GTP			1e-3		1e-3		1e-3		1e-3	1e-3		1e-3
	Reaction		Complex CAS with NPC(c)	kr	1/s				1e-5		1e-5		1e-5		1e-5	1e-5		1e-5
	Reaction		Complex CAS with NPC(n)	kf	1/uM/s				1e-3		1e-3		1e-3		1e-3	1e-3		1e-3
	Reaction		Complex CAS with NPC(n)	kr	1/s				1e-5		1e-5		1e-5		1e-5	1e-5		1e-5
	Reaction		Replenish NLS	kf	1/s				0		0		0		0	0		0
	Reaction		Passive diffusion	k_diff	1/s				0		0		0		0	0		0
	Reaction		Ran gradient	k_pump	1/s				0.1		0.1		0.1		0.1	0.1		0
			For uploaded results, see:
			https://numpde.github.io/nct1/code/20211018-Appli/checkpoint/